发明名称 |
USE OF ALKANOYL L-CARNITINE IN COMBINATION WITH CHEMOTHERAPEUTIC AGENTS FOR THE TREATMENT OF NEOPLASMS |
摘要 |
<p>The present invention relates to the use of an alkanoyl L-carnitine selected from the group consisting of acetyl, propionyl, valeryl, isovaleryl and butirryl L-carnitine; in combination with one or more chemotherapeutic agent selected from the group consisting of: a camptothecin derivative; an alkylating agent; an anti-neoplastic anti-metabolite; a platin compound; a topoisomerase inhibitor; a VEGF inhibitor; a tyrosine kinase inhibitor; an EGFR kinase inhibitor; an mTOR kinase inhibitor; an insulin-like growth factor I inhibitor; a Raf kinase inhibitor; a monoclonal antibody; a proteasome inhibitor; a HDAC inhibitor; toxins; and imides; for the treatment of neoplasms.</p> |
申请公布号 |
WO2010063696(A1) |
申请公布日期 |
2010.06.10 |
申请号 |
WO2009EP66113 |
申请日期 |
2009.12.01 |
申请人 |
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A.;CAVAZZA, CLAUDIO;CARMINATI, PAOLO;PISANO, CLAUDIO |
发明人 |
CAVAZZA, CLAUDIO;CARMINATI, PAOLO;PISANO, CLAUDIO |
分类号 |
A61K31/205;A61K31/282;A61K31/337;A61K31/427;A61K31/4745;A61K31/475;A61K31/513;A61K31/555;A61K38/14;A61P35/00 |
主分类号 |
A61K31/205 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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