发明名称 |
MAINTENANCE/EXPANSION OF HSCs |
摘要 |
The invention is related to methods for culturing stem cells, more particularly hematopoietic stem cells (HSC). The invention relates to methods for HSC maintenance and/or expansion through the use of soluble factors. The invention is also directed to cells produced by the methods of the invention. The cells are useful, among other things, for treatment of disorders or diseases (e.g. leukemia). The invention also relates to the development of small molecules that may increase HSC self renewal in vitro and in vivo. |
申请公布号 |
WO2010065546(A2) |
申请公布日期 |
2010.06.10 |
申请号 |
WO2009US66271 |
申请日期 |
2009.12.01 |
申请人 |
VERFAILLIE, CATHERINE;BUCKLEY, SHANNON MYCHEL |
发明人 |
VERFAILLIE, CATHERINE;BUCKLEY, SHANNON MYCHEL |
分类号 |
C12N5/0789;C07K14/52 |
主分类号 |
C12N5/0789 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|