发明名称 |
CONTROLLED DRUG RELEASE SYSTEM BY FLUORINATION BASED ON BIODEGRADABLE NANO-FIBERS AND MANUFACTURING METHOD THEREOF |
摘要 |
PURPOSE: A method for manufacturing biodegradable nanofibers having a controlled drug release system by fluorination is provided to control the output rate of a drug contained within the nanofiber by introducing a hydrophobic functional group on the surface of the nanofibers, formed through an electrospinning and a radiation process. CONSTITUTION: A method for manufacturing biodegradable nanofibers having a controlled drug release system by fluorination comprises the following steps: mixing a polymer precursor, a water soluble drug, and a solvent together; obtaining the nanofibers by electrospinning the mixture; cross-linking the nanofibers through a radiation process; and modifying the surface of the cross-linked nanofibers. The polymer precursor is a biodegradable polymer. |
申请公布号 |
KR20100058733(A) |
申请公布日期 |
2010.06.04 |
申请号 |
KR20080117238 |
申请日期 |
2008.11.25 |
申请人 |
THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (IAC) |
发明人 |
LEE, YOUNG SEAK;IM, JI SUN;LIM, JAE WON |
分类号 |
B82B3/00;B82B1/00;D01D5/00;D01F1/10 |
主分类号 |
B82B3/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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