NUCLEIC ACID DELIVERY COMPOSITIONS AND METHODS

摘要

Complexes comprising a cationic polymer, a nucleic acid and a metal ion are provided. In some embodiments, a complex may be used as a means for delivering nucleic acid to a cell. In some embodiments, a complex may be used as part of a gene therapy. Methods of making a complex comprising a cationic polymer, a nucleic acid, and a metal ion are also described. Methods of condensing a polyplex comprising a cationic polymer and a nucleic acid are also provided.