| 摘要 |
The invention relates to methods of T cell immune system modulation and the treatment of immune system related diseases and disorders. In particularly, embodiments of the invention provides immunotherapeutics in the form of antibodies, bioengmeered antibodies and recombinant proteins for the treatment of autoimmune diseases and disorders, organ transplantation rejection, graft-versus-host tissue diseases, and T-cell based lymphoma and leukemia.
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