MARKER ASSISTED SELECTION OF A MAMMALIAN SUBJECT FOR DESIRED IMMUNOGLOBULIN PHENOTYPE

摘要

The present invention provides methods of identifying or selecting mammalian subjects having one or more desired immunoglobulin phenotype(s) by determining a PIGR genotype of the subject. Particularly contemplated are methods of identifying or selecting bovine wherein the presence or absence of the G allele or the C allele at the C903G polymorphism in the bovine PIGR gene, or the presence or absence of the G allele or the A allele at the A3938G polymorphism in the bovine PIGR gene, or the presence or absence of the G allele or the A allele at the A4029G polymorphism in the bovine PIGR gene, or the presence or absence of the G allele or the A allele at the G5183A polymorphism in the bovine PIGR gene, is associated with variation in milk or colostrum immunoglobulin content.