发明名称 |
METAP-2 INHIBITOR POLYMERSOMES FOR THERAPEUTIC ADMINISTRATION |
摘要 |
The present invention provides methods to treating inflammation related disease and disorders such as an autoimmune disease and autoimmune related uveitis by administering compositions and formulations comprising MetAP-2 inhibitors as disclosed herein. The composition comprises a formulation of a fumagillol derivative that retains anti-inflammation activity and is associated with a block copolymer comprising a hydrophilic polymer moiety and a hydrophobic polymer moiety. |
申请公布号 |
EP2170402(A2) |
申请公布日期 |
2010.04.07 |
申请号 |
EP20080772043 |
申请日期 |
2008.06.26 |
申请人 |
CHILDREN'S MEDICAL CENTER CORPORATION |
发明人 |
BENNY-RATSABY, OFRA;FOLKMAN, JUDAH |
分类号 |
A61K47/48;A61P35/00 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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