发明名称 Spiro-piperidine derivatives
摘要 The present invention is concerned with novel spiro-piperidine derivatives as V1a receptor antagonists, their manufacture, pharmaceutical compositions containing them and their use as medicaments. The active compounds of the present invention are useful in the prevention and/or treatment of anxiety and depressive disorders and other diseases. In particular, the present invention is concerned with compounds of the general formula (I) wherein R1 to R5, R5′, X, Y and A are as defined in the specification.
申请公布号 US7678806(B2) 申请公布日期 2010.03.16
申请号 US20070955434 申请日期 2007.12.13
申请人 HOFFMANN-LA ROCHE INC. 发明人 BISSANTZ CATERINA;GRUNDSCHOBER CHRISTOPHE;MASCIADRI RAFFAELLO;RATNI HASANE;ROGERS-EVANS MARK;SCHNIDER PATRICK
分类号 A61K31/438;C07D471/10 主分类号 A61K31/438
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