发明名称 |
Experimental models of age-related macular degeneration and related retinal disorders |
摘要 |
The present invention relates to experimental models of age-related macular degeneration (AMD) and related retinal disorders and to screening methods using these models for detecting molecule candidates for the treatment of AMD. In particular, the present invention relates to the use of an animal or a cell that is deficient in functional Niemann Pick type C-related protein as experimental model of AMD and vision disorders resulting from AMD. The present invention founds industrial applications for preclinical research and development on age-related macular degeneration and similar diseases. Examples of potential industrial application are in companies that have a preclinical R&D program in retinal diseases, particularly in AMD. |
申请公布号 |
EP2161330(A1) |
申请公布日期 |
2010.03.10 |
申请号 |
EP20080290808 |
申请日期 |
2008.08.28 |
申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS;UNIVERSITE LOUIS PASTEUR |
发明人 |
PFRIEGER, FRANK W.;CLAUDEPIERRE, THOMAS |
分类号 |
C07K14/47;A01K67/027;C12N5/00 |
主分类号 |
C07K14/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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