发明名称 MELK EPITOPE PEPTIDES AND VACCINES CONTAINING THE SAME
摘要 According to the present invention, peptides having the amino acid sequence of SEQ ID NOs: 14, 21, 23, 27, 36, 46, 57, 60 and 62 were demonstrated to have cytotoxic T lymphocyte (CTL) inducibility. Therefore, the present invention provides a peptide having the amino acid sequence selected from among SEQ ID NOs: 14, 21, 23, 27, 36, 46, 57, 60 and 62. The peptide can include one, two, or several amino acid substitutions, deletions, insertions, or additions so long as its CTL inducibility is retained. Furthermore, the present invention provides pharmaceutical agents for the treatment and/or prophylaxis of cancers, and/or prevention of postoperative recurrence thereof, which contain any of these peptides. Pharmaceutical agents of this invention include vaccines.
申请公布号 WO2010013485(A1) 申请公布日期 2010.02.04
申请号 WO2009JP03630 申请日期 2009.07.30
申请人 ONCOTHERAPY SCIENCE, INC.;TSUNODA, TAKUYA;OHSAWA, RYUJI 发明人 TSUNODA, TAKUYA;OHSAWA, RYUJI
分类号 C07K7/06;C12N15/09;A61K38/00;A61K38/08;A61K39/00;A61P35/00;C12N5/10;C12N15/11;C12Q1/02;G01N33/566 主分类号 C07K7/06
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