The invention provides compounds of Formula (I) for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds. The invention also provides methods of treating diseases and disorders related to deficiency or overexpression of O-GlcNAcase, accumulation or deficiency of O-GlcNAc.
申请公布号
WO2010012106(A1)
申请公布日期
2010.02.04
申请号
WO2009CA01087
申请日期
2009.07.31
申请人
SIMON FRASER UNIVERSITY;VOCADLO, DAVID, JARO;MCEACHERN, ERNEST JOHN;STUBBS, KEITH
发明人
VOCADLO, DAVID, JARO;MCEACHERN, ERNEST JOHN;STUBBS, KEITH