发明名称 |
Thiazole compound and use thereof |
摘要 |
Thiazole compounds for inhibiting the activity of phosphodiesterase 4, the production of tumor necrosis factor alpha, and the production of interleukin 4. The compounds of the invention are represented by general formula (1): wherein A is any one of the following groups (i) and (ii): (i) -CO-B- wherein B is a C1-6 alkylene group and (ii) -CO-Ba- wherein Ba is a C2-6 alkenylene group, and include optical isomers and salts of the compounds.
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申请公布号 |
US7655680(B2) |
申请公布日期 |
2010.02.02 |
申请号 |
US20070587862 |
申请日期 |
2007.07.05 |
申请人 |
OTSUKA PHARMACEUTICAL CO., LTD. |
发明人 |
TAKEMURA ISAO;WATANABE KENJI;OSHIMA KUNIO;ITO NOBUAKI;HARUTA JUNPEI;HIYAMA HIDETAKA;CHIHIRO MASATOSHI;KAWASOME HIDEKI;SAKAMOTO YOKO;ISHIYAMA HIRONOBU;SUMIDA TAKUMI;FUJITA KAZUHIKO;KITAGAKI HIDEKI |
分类号 |
A61K31/425;A61K31/426;A61K31/427;A61K31/4439;A61K31/4709;A61K31/496;A61K31/497;A61K31/498;A61K31/506;A61K31/5377;A61P17/00;A61P43/00;C07D277/20;C07D277/24;C07D277/30;C07D277/56;C07D417/06;C07D495/04 |
主分类号 |
A61K31/425 |
代理机构 |
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代理人 |
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地址 |
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