| 发明名称 |
PEPTIDE INHIBITORS OF NUCLEAR PROTEIN TRANSLOCATION HAVING NUCLEAR LOCALIZATION SEQUENCES AND METHODS OF USE THEREOF |
| 摘要 |
Novel polypeptide inhibitors of cytoplasmic protein nuclear translocation are disclosed. The inhibitors are comprised of a signal sequence and at least two nuclear localization sequences. The polypeptides are useful as immunosuppression, antiviral and antitumor agents.
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| 申请公布号 |
CA2265571(A1) |
申请公布日期 |
1998.03.26 |
| 申请号 |
CA19972265571 |
申请日期 |
1997.09.15 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
NADLER, STEVEN G.;BLAKE, JAMES;HAFFAR, OMAR K.;CLEAVELAND, JEFFREY S. |
| 分类号 |
C12N15/09;A61K38/00;A61K45/06;A61P31/12;A61P35/00;A61P37/06;C07K7/06;C07K7/08;C07K14/00;C07K14/47;(IPC1-7):C07K7/06;A61K38/02;A61K38/08;A61K38/10;A61K38/16 |
主分类号 |
C12N15/09 |
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