发明名称 |
СПОСОБЫ ПОЛУЧЕНИЯ РАСТВОРИМЫХ МНОГОПРОХОДНЫХ ТРАНСМЕМБРАННЫХ БЕЛКОВ |
摘要 |
Methods for producing membrane-spanning polypeptides in high yields, with native conformation, and/or in soluble form include solubilizing in non-ionic or zwitterionic detergents as well as use of promoters and expression vectors for expressing high yields of membrane-spanning polypeptides in bacterial cells. Mutated promoters provide tight control of membrane-spanning polypeptides in bacterial cell hosts. |
申请公布号 |
RU2007127812(A) |
申请公布日期 |
2009.01.27 |
申请号 |
RU20070127812 |
申请日期 |
2005.12.22 |
申请人 |
ДЖЕНЕНТЕК, ИНК. (US) |
发明人 |
ЭРНСТ Джеймс А. (US);ЯНСУРА Дэниэл Г. (US);КИМ Хок Сеон (US) |
分类号 |
C12N15/70;C07K1/14;C07K14/705;C07K16/18;C12N1/21;C12N15/11;C12N15/12;G01N33/531 |
主分类号 |
C12N15/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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