发明名称 |
METHOD FOR PRODUCTION OF INSOLUBLE CARRIER PARTICLE, INSOLUBLE CARRIER PARTICLE, MEASUREMENT REAGENT, SAMPLE ANALYSIS TOOL, AND IMMUNOLOGY TURBIDIMETRIC METHOD |
摘要 |
<p>Disclosed are: a measurement reagent which is not non-specifically aggregated even when the quantity of antibodies carried on the reagent is increased, can achieve the measurement in a wide concentration range, and has high measurement sensitivity; an immunology turbidimetric method using the measurement reagent; and a method for producing the measurement reagent. Specifically disclosed is a method for producing an insoluble carrier particle, which is a method for producing an insoluble carrier particle having an antibody or antigen carried on the surface thereof. The method comprises a sensitization reaction step of contacting the insoluble carrier particle with the antibody or antigen in a sensitization reaction solution in the presence of a polar charged side-chain amino acid. The insoluble carrier particle produced by the method is not non-specifically aggregated, and therefore has excellent dispersibility. As shown in Examples 1-1 to 1-4 in Fig. 3, the insoluble carrier particle can achieve the measurement in a wide concentration range and has high measurement sensitivity when used in the measurement by an immunology turbidimetric method.</p> |
申请公布号 |
WO2009136541(A1) |
申请公布日期 |
2009.11.12 |
申请号 |
WO2009JP57903 |
申请日期 |
2009.04.21 |
申请人 |
ARKRAY, INC.;TAKAGI, HIDENORI |
发明人 |
TAKAGI, HIDENORI |
分类号 |
G01N33/543;G01N33/545 |
主分类号 |
G01N33/543 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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