USE OF SIRNA TO ACHIEVE DOWN REGULATION OF AN ENDOGENOUS GENE IN COMBINATION WITH THE USE OF A SENSE CONSTRUCT TO ACHIEVE EXPRESSION OF A DESIRED POLYNUCLEOTIDE
摘要
The present invention relates to the combinatorial use of an siRNA targeted against an endogenous gene to knock out or knock down expression of the endogenous gene in a host and a delivery of a polynucleotide encoding the gene in a delivery vehicle/expression vector to the host to provide expression in the host of the protein encoded by the polynucleotide.
申请公布号
WO2009114487(A3)
申请公布日期
2009.11.05
申请号
WO2009US36583
申请日期
2009.03.09
申请人
SENESCO TECHNOLOGIES, INC.;DONDERO, RICHARD S.;THOMPSON, JOHN E.;TAYLOR, CATHERINE A.