发明名称 |
LONG LASTING NATRIURETIC PEPTIDE DERIVATIVES |
摘要 |
This invention relates to long lasting natriuretic peptide (NP) derivatives. The NP derivative has a NP peptide and a reactive entity coupled to the NP peptide. The reactive entity is able to covalently bond with a functionality on a blood component. In particular, this invention relates to NP derivatives having an extended in vivo half-life, and method for the treatment of cardiovascular diseases and disorders such as acute decompensated congestive heart failure (CHF) and chronic CHF.
|
申请公布号 |
US2009275506(A1) |
申请公布日期 |
2009.11.05 |
申请号 |
US20080253856 |
申请日期 |
2008.10.17 |
申请人 |
CONJUCHEM BIOTECHNOLOGIES, INC. |
发明人 |
BAKIS PETER;BRIDON DOMINIQUE P.;CARETTE JULIE;LECLAIRE FRANCE;LEGER ROGER;ROBITAILLE MARTIN |
分类号 |
A61K38/16;A61K38/17;C07K1/00;C07K7/08;C07K14/00;C07K14/47 |
主分类号 |
A61K38/16 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|