摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a compound useful for treating various metabolic disorders such as insulin-resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis, and arteriosclerosis. <P>SOLUTION: The compound is a medical agent, which is a biologically active agent, is represented by the following formula or is a pharmaceutically receptible salt of the above represented compound. In the formula, n is 1 or 2; m is 0 or 1; q is 0 or 1; t is 0 or 1; R<SP>9</SP>is hydrogen, halo-, or 1-3C alkoxy; and X is -CH<SB>2</SB>- and Q is -OR<SP>1</SP>, or X is -CH<SB>2</SB>CR<SP>12</SP>CR<SP>13</SP>- or CH<SB>2</SB>CH(NHAc)- and Q is OR<SP>1</SP>, or X is -CH<SB>2</SB>CH<SB>2</SB>- and Q is NR<SP>10</SP>R<SP>11</SP>. <P>COPYRIGHT: (C)2010,JPO&INPIT</p> |