| 发明名称 |
Compounds for Nonsense Suppression, and Methods for Their Use |
| 摘要 |
The present invention relates to methods, compounds, and compositions for treating or preventing diseases associated with nonsense mutations in an mRNA by administering the compounds or compositions of the present invention. More particularly, the present invention relates to methods, compounds, and compositions for suppressing premature translation termination associated with a nonsense mutation in an mRNA.
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| 申请公布号 |
US2009253699(A1) |
申请公布日期 |
2009.10.08 |
| 申请号 |
US20050577191 |
申请日期 |
2005.10.13 |
| 申请人 |
PCT THERAPEUTICS, INC. |
发明人 |
ALMSTEAD NEIL G.;CHEN GUANGMING;KARP GARY M.;WELCH ELLEN;WILDE RICHARD;CAMPBELL JEFFREY A. |
| 分类号 |
A61K31/5377;A61K31/34;A61K31/415;A61K31/421;A61K31/4245;A61K31/426;A61K31/433;A61P7/00;A61P9/00;A61P25/00;A61P29/00;A61P37/06;C07D231/10;C07D263/30;C07D271/10;C07D277/20;C07D285/12;C07D307/02;C07D413/02;C12N5/00 |
主分类号 |
A61K31/5377 |
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