摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide useful compounds for treatments of various metabolic disturbances (for example, insulin resistant syndromes, diabetes mellitus, hyperlipidemia, fatty liver diseases, cachexia, obesity, atherosclerosis and arterial sclerosis). <P>SOLUTION: Biologically active drugs, namely the drugs are compounds shown by formula I or their pharmaceutically acceptable salts, wherein n represents 1 or 2, m represents 0 or 1, q represents 0 or 1, t represents 0 or 1, R<SP>9</SP>represents a hydrogen, a halogen or 1-3C alkoxy, X represents -CH<SB>2</SB>- and Q represents -OR<SP>1</SP>, or X represents -CH<SB>2</SB>CR<SP>12</SP>CR<SP>13</SP>- or -CH<SB>2</SB>CH(NHAc)- and Q represents -OR<SP>1</SP>, or X represents -CH<SB>2</SB>CH<SB>2</SB>- and Q represents NR<SP>10</SP>R<SP>11</SP>. <P>COPYRIGHT: (C)2010,JPO&INPIT</p> |