| 发明名称 |
Modulation of exon recognition in pre-mRNA by interfering with the secondary RNA structure |
| 摘要 |
The invention relates to oligonucleotides for inducing skipping of exon 53 of the dystrophin gene. The invention also relates to methods of inducing exon 53 skipping using the oligonucleotides. |
| 申请公布号 |
AU2004221495(B2) |
申请公布日期 |
2009.08.27 |
| 申请号 |
AU20040221495 |
申请日期 |
2004.03.22 |
| 申请人 |
ACADEMISCH ZIEKENHUIS LEIDEN |
发明人 |
JUDITH CHRISTINA THEODORA VAN DEUTEKOM;ANNEMIEKE AARTSMA-RUS;JOHANNES THEODORUS DEN DUNNEN;GARRIT-JAN BOUDEWIJN VAN OMMEN |
| 分类号 |
A61K38/00;A61K48/00;C12N15/113 |
主分类号 |
A61K38/00 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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