Use of Phosphodiesterase Inhibitor as a Component of Implantable Medical Devices

摘要

Implantable medical devices having coatings comprising phosphodiesterase inhibitors are disclosed. Specifically, coatings comprising phosphodiesterase-5 inhibitors are disclosed. The phosphodiesterase-5 inhibitors include sildenafil, tadalafil, vardenafil or pharmaceutically acceptable derivatives thereof. The medical devices can include stents, catheters, micro-particles, probes and grafts