| 发明名称 |
PROCESS FOR PREPARING THE ANTIVIRAL AGENT [1S-(1ALPHA,3ALPHA,4BETA)]-2-AMINO-1,9-DIHYDRO-9-[4-HYDROXY-3-(HYDROXYMETHYL)-2-METHYLENECYCLOPENTYL]-6H-PURIN-6-ONE |
| 摘要 |
<p>Processes are disclosed for preparing the antiviral agent entecavir. A resin adsorption process for the isolation and purification of entecavir is also disclosed. Various intermediates useful in the preparation of entecavir are also disclosed. ® KIPO & WIPO 2009</p> |
| 申请公布号 |
KR20090084979(A) |
申请公布日期 |
2009.08.05 |
| 申请号 |
KR20097015624 |
申请日期 |
2003.12.10 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
PENDRI YADAGIRI R.;CHEN CHUNG PIN H.;PATEL SUNIL S.;EVANS JEFFREY M.;LIANG JING;KRONENTHAL DAVID R.;POWERS GERALD L.;PRASAD SIVA JOSYULA;BIEN JEFFREY T.;SHI ZHONGPING;PATEL RAMESH N.;CHAN YEUNG Y.;RIJHWANI SUSHIL K.;SINGH AMBARISH K.;WANG SHAOPENG;STOJANOVIC MILAN;POLNIASZEK RICHARD;LEWIS CHARLES;THOTTATHIL JOHN;KRISHNAMURTY DHILEEPKUMAR;ZHOU MAOTANG X.;VEMISHETTI PURUSHOTHAM;BANERJEE AMIT;KUCERA DAVID J. |
| 分类号 |
C07D473/18;C07D473/02;C07D473/12;C07F7/08;C07F7/18 |
主分类号 |
C07D473/18 |
| 代理机构 |
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