| 摘要 |
Ex-vivo procedure for increasing the efficacy of active substances binding to antibodies and Fcgamma -receptors, comprises: (a) preparing a blood sample of a patient; (b) subjecting the blood sample to an immunophoresis; and (c) administering an antibody or an Fcgamma -receptor binding active substance to a patient. Independent claims are included for: (1) use of a combination of one or more medicaments with FcR-binding immunoglobulins, fragments of immunoglobulin or fusion proteins, for producing a medicament for treating cancer, autoimmune diseases, transplanted patients and/or for vaccinating against viruses, where the treatment comprises preparing a blood sample of a patient, subjecting the blood sample to an immunophoresis and administering an antibody to a patient; (2) use of specific ligands for body's own antibodies with Fcgamma -receptor binding regions, for producing a column, which exhibits the specific ligand that is coupled to it, for treating a patient with Fcgamma -receptor binding active substances, where the treatment comprises preparing a blood sample of a patient, subjecting the blood sample to an immunophoresis and administering Fcgamma -receptor binding active substances to a patient; (3) use of specific ligands for body's own antibodies for producing a column, which exhibits the ligand that is coupled to it, for treating a patient with antibodies, where the treatment comprises: (a) preparing a blood sample of a patient; (b) subjecting the blood sample to an immunophoresis; (c) administering an antibody to a patient; (4) use of specific ligands for cancer-associated antigens soluble in blood sample for producing a column, which exhibits the ligand that is coupled to it, for treating a patient with therapeutic antibodies, where the treatment comprises preparing a blood sample of a patient, subjecting the blood sample to an immunophoresis and administering an antibody to a patient; and (5) use of Fcgamma -receptor binding active substances for producing a medicaments for treating cancer, autoimmune diseases, transplanted patients and/or for vaccinating against viruses, where the treatment comprises preparing a blood sample of a patient, subjecting the blood sample to a immunophoresis and administering the medicament to the patients. ACTIVITY : Cytostatic; Immunosuppressive. MECHANISM OF ACTION : None given. |
