发明名称 ETHER DERIVATIVES DUAL MODULATORS OF THE 5-HT2A AND D3 RECEPTORS
摘要 The present invention relates to dual modulators of the serotonin 5-HT2a and dopamine D3 receptors which are represented by the general formula (I) wherein R1, R2 and A are as defined in the specification, to a process for the manufacture thereof, as well as to pharmaceutically acceptable salts thereof for the manufacture of a medicament for the treatment or prevention of cognitive disorders, drug addiction, depression, anxiety, drug dependence, dementias, memory impairment, psychotic disorders comprising schizophrenia, schizoaffective disorders, bipolar disease, mania, psychotic depression, and psychoses comprising paranoia and delusions.
申请公布号 KR20090075848(A) 申请公布日期 2009.07.09
申请号 KR20097008855 申请日期 2007.10.22
申请人 F. HOFFMANN-LA ROCHE AG 发明人 GOBBI LUCA CLAUDIO;JAESCHKE GEORG;ROCHE OLIVIER;RODRIGUEZ SARMIENTO ROSA MARIA;STEWARD LUCINDA
分类号 C07D403/12;A61K31/445;C07D405/12;C07D409/12 主分类号 C07D403/12
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