发明名称 ADIPONECTIN RECEPTOR FRAGMENTS AND METHODS OF USE
摘要 Methods are disclosed of treating diabetes, abnormal adipocyte activity, and insulin resistance using C-terminal fragments of adiponectin receptor R1. Methods of causing the secretion of insulin in healthy and diabetic patients using C-terminal fragments of adiponectin receptor R1 are also disclosed. In addition, methods are disclosed of increasing the insulin levels in healthy patients using C-terminal fragments of adiponectin receptor R1. In addition, methods of treating abnormal adipocyte activity, treating metabolic syndrome, causing insulin secretion, increasing insulin levels, inhibiting insulin degradation enzyme, treating Alzheimer's disease, treating cardiovascular disease associated with adiponectin levels, inhibiting ADAM- 17 enzyme, treating a condition associated with TNF-alpha, and treating a condition associated with HER2- neu are disclosed. Compositions, dosage forms, and kits are also disclosed.
申请公布号 WO2009070350(A1) 申请公布日期 2009.06.04
申请号 WO2008US69500 申请日期 2008.07.09
申请人 SIEMENS HEALTHCARE DIAGNOSTICS INC.;PUGIA, MICHAEL;MA, RUI 发明人 PUGIA, MICHAEL;MA, RUI
分类号 C12Q1/68 主分类号 C12Q1/68
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