发明名称 |
LDL-LIKE CATIONIC NANOPARTICLES FOR DELIVERYING NUCLEIC ACID GENE, METHOD FOR PREPARING THEREOF AND METHOD FOR DELIVERYING NUCLEIC ACID GENE USING THE SAME |
摘要 |
Disclosed are a LDL-like cationic nanoparticle for delivering a nucleic acid gene with improved transfection efficiency and stability, which is surface modified and re-constructed by mimicking lipid components of a natural LDL, a method for preparation of the same, and a method for delivering nucleic acid genes using the same. The cationic nanoparticle of the present invention could effectively be applied in treatment of cancer that overexpress LDL receptors. |
申请公布号 |
WO2009051451(A3) |
申请公布日期 |
2009.06.04 |
申请号 |
WO2008KR06167 |
申请日期 |
2008.10.17 |
申请人 |
KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY;PARK, TAE-GWAN;KIM, HYUN-RYOUNG;KIM, IN-KYOUNG |
发明人 |
PARK, TAE-GWAN;KIM, HYUN-RYOUNG;KIM, IN-KYOUNG |
分类号 |
A61K9/51 |
主分类号 |
A61K9/51 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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