发明名称 |
PEPTIDES WITH CAPACITY TO BIND TO SCURFIN AND APPLICATIONS |
摘要 |
The invention relates to peptides of general formula (I), wherein X is absent or X is present and is X14 or X14-X15, wherein X14 and X15 independently from one another, represent an amino acid; their functional variants and fragments, and their pharmaceutically acceptable salts, having the capacity to bind to scurfin and inhibit its biological activity, therefore they regulate or block the activity of regulatory T (Treg) lymphocytes. They are applicable in the treatment of infectious and neoplastic diseases. Arg-Asp-Phe-Gln-Ser-Phe-Arg-Lys-Met-Trp-Pro-Phe-Phe-X (I)
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申请公布号 |
CA2706201(A1) |
申请公布日期 |
2009.05.28 |
申请号 |
CA20082706201 |
申请日期 |
2008.11.14 |
申请人 |
PROYECTO DE BIOMEDICINA CIMA, S.L. |
发明人 |
CASARES LAGAR, INES NOELIA;BORRAS CUESTA, FRANCISCO;SAROBE UGARRIZA, PABLO;PRIETO VALTUENA, JESUS;LASARTE SAGASTIBELZA, JUAN JOSE |
分类号 |
C07K7/08;A61K38/10;A61K39/39;A61K47/48;A61P31/00;A61P31/14;A61P35/00;C07K19/00;C12N5/0783;C12N15/62 |
主分类号 |
C07K7/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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