| 发明名称 |
N-BIPHENYLMETHYL AMINOCYCLOALKANECARBOXAMIDE DERIVATIVES WITH A SUBSTITUENT ON THE METHYL USEFUL AS BRADYKININ ANTAGONISTS |
| 摘要 |
N-Biphenyl(substituted methyl)aminocycloalkanecarboxamide derivatives are bradykinin B1 antagonists or inverse agonists useful in the treatment or prevention of symptoms such as pain and inflammation associated with the bradykinin B1 pathway.
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| 申请公布号 |
CA2474373(C) |
申请公布日期 |
2009.05.26 |
| 申请号 |
CA20032474373 |
申请日期 |
2003.02.04 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
FENG, DONG-MEI;BOCK, MARK G.;ANTHONY, NEVILLE J.;KUDUK, SCOTT D.;WAI, JENNY MIU-CHUN;SU, DAI-SHI;WOOD, MICHAEL R. |
| 分类号 |
C07C237/24;A61K31/166;A61K31/24;A61K31/41;A61K31/42;A61K31/4245;A61K31/505;A61P1/02;A61P1/04;A61P1/16;A61P1/18;A61P9/10;A61P11/00;A61P11/06;A61P11/08;A61P13/10;A61P13/12;A61P17/02;A61P17/06;A61P19/02;A61P19/08;A61P21/00;A61P25/04;A61P25/06;A61P25/28;A61P27/16;A61P29/00;A61P31/04;A61P35/00;A61P37/08;C07D213/82;C07D239/28;C07D257/04;C07D261/18;C07D271/06;C07D403/12;C07D413/12 |
主分类号 |
C07C237/24 |
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