PLATINUM COMPOSITIONS AS TREATMENT FOR OCT-RELATED CANCERS

摘要

The present invention provides compositions, preparations, formulations, kits, and methods useful for treating subjects having cancer or at risk of developing cancer, in some cases, cancers which express an organic cation transporter (OCT). Some embodiments of the invention may comprise a compound including platinum (e.g., platinum(II) or platinum(IV)) and at least one organic ligand. In some embodiments, the compound may comprise an organic ligand which enhances interaction between the compound and an OCT.