发明名称 |
Biomarker for the prediction of responsiveness to an anti-tumour necrosis factor alpha (TNF) treatment |
摘要 |
<p>The invention refers to a method for diagnosing an individual who is to be subjected to or is being subjected to an anti-tumour necrosis factor alpha (TNF± or TNF) treatment to asses the responsiveness to an anti-TNF treatment which comprises the detection of immunoglobulin(s) against one or more biomarker proteins in a bodily fluid or an excrement of said patient, and sorting the individual into one of two categories based on detection of said immunoglobulin(s), wherein individuals are classified as NON-responder or responder. The invention refers to diagnostic kits comprising said one or more biomarker proteins and the use of these kits for assessing the responsiveness to an anti-TNF treatment of an individual who is to be subjected to or is being subjected to an anti-TNF± treatment.</p> |
申请公布号 |
EP2056110(A1) |
申请公布日期 |
2009.05.06 |
申请号 |
EP20070119810 |
申请日期 |
2007.10.31 |
申请人 |
MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. |
发明人 |
KONTHUR, ZOLTHAN;LEHRACH, HANS |
分类号 |
G01N33/564;G01N33/68 |
主分类号 |
G01N33/564 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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