NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID

摘要

[PROBLEMS] To provide: a compound effective as an amyloid-targeting diagnostic imaging probe; and a reagent for detecting amyloid deposited on a biological tissue, which comprises the compound. [MEANS FOR SOLVING PROBLEMS] Disclosed are: a compound represented by the formula shown below; and a reagent for detecting amyloid deposited on a biological tissue, which comprises the compound (1). Wherein R1, R2 and R3 independently represent a group selected from the group consisting of a hydrogen, a hydroxyl group, an alkyl substituent having 1 to 4 carbon atoms, an alkoxy substituent having 1 to 4 carbon atoms in its alkyl chain, and a halogen substituent (provided that all of at least two substituents selected from R1, R2 and R3 cannot represent a hydrogen); R4 represents a group selected from the group consisting of a hydrogen, a hydroxyl group, an alkoxy substituent having 1 to 4 carbon atoms in its alkyl chain, a halogen substituent; and m represents an integer of 1 to 4, provided that at least one of R1, R2, R3 and R4 represents a radioactive halogen substituent.