A process for the synthesis of perindopril and the pharmaceutically-acceptable salts thereof

摘要

A process for the synthesis of perindopril of formula (I) and its pharmaceutically acceptable salts is disclosed. Perindopril and its pharmaceutically acceptable salts, and more especially its tertbutylamine salt, have valuable pharmacological properties, which contribute to the beneficial effects of perindopril in cardiovascular diseases, more especially in arterial hypertension and heart failure.