发明名称 |
USE OF THE OPPOSITE CELL DIFFERENTIATION PROGRAM (OCDP) FOR THE TREATMENT OF DEGENERATED ORGANS IN THE PATHOLOGICAL STATE |
摘要 |
<p num="1">The present invention relates to a method for the treatment of organs which are degenerative and /or in the pathological state by means of the use of cells, which are phenotypically stably differentiating or differentiated but not necessarily ultimately predetermined with respect to development, from a donor organ selected according to the principles of the opposite cell differentiation program (OCDP) and also to the use of cells of this type for the treatment or for the production of a drug for treatment of the same. Furthermore, the present invention relates to pharmaceutical agents comprising suitable phenotypically stable cells, cells of a first organ which is different from the second organ with respect to organ type thereby being used, which, in the normal physiological state with respect to a predetermined set of expressed genes and/ or phenotypical properties, have opposite properties to the second cells in the normal physiological state. </p> |
申请公布号 |
CA2699624(A1) |
申请公布日期 |
2009.03.26 |
申请号 |
CA20082699624 |
申请日期 |
2008.04.18 |
申请人 |
UNIVERSITAT LEIPZIG |
发明人 |
BUNIATIAN, GAYANE;GEBHARDT, ROLF;GLEITER, CHRISTOPH;DANIELYAN, LUSINE;PROKSCH, BARBARA |
分类号 |
A61K35/37;A61K35/12;C12N5/071;C12N5/079 |
主分类号 |
A61K35/37 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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