| 发明名称 |
INHIBITORS OF THE INTERACTION BETWEEN MDM2 AND P53 |
| 摘要 |
<p>The present invention provides compounds of formula (I), their use as an inhibitor of a p53-MDM2 interaction as well as pharmaceutical compositions comprising said compounds: wherein n, s, t, R1, R2, R3, R4, R5, X, Y, Q, Z, G, E and D have defined meanings.</p> |
| 申请公布号 |
WO2009037343(A1) |
申请公布日期 |
2009.03.26 |
| 申请号 |
WO2008EP62551 |
申请日期 |
2008.09.19 |
| 申请人 |
JANSSEN PHARMACEUTICA NV;STORCK, PIERRE-HENRI;SCHOENTJES, BRUNO;PIETTRE, ARNAUD MARCEL PIERRE;ERMERT, PHILIPP;PONCELET, VIRGINIE SOPHIE;CSOKA, IMRE CHRISTIAN FRANCIS |
发明人 |
STORCK, PIERRE-HENRI;SCHOENTJES, BRUNO;PIETTRE, ARNAUD MARCEL PIERRE;ERMERT, PHILIPP;PONCELET, VIRGINIE SOPHIE;CSOKA, IMRE CHRISTIAN FRANCIS |
| 分类号 |
C07D413/14;A61K31/538;A61P35/00 |
主分类号 |
C07D413/14 |
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