PROCESSES FOR THE PREPARATION OF A LINEZOLID INTERMEDIATE, LINEZOLID HYDROXIDE
摘要
Provided are methods for the enantiomeric purification of Linezolid hydroxide, comprising providing a solution or a slurry of Linezolid hydroxide and a solvent selected from alcohols and ketones and crystallizing Linezolid hydroxide from the solution or slurry to obtain Linezolid hydroxide with a low content of S isomer.
申请公布号
WO2009032294(A2)
申请公布日期
2009.03.12
申请号
WO2008US10397
申请日期
2008.09.05
申请人
TEVA PHARMACEUTICAL INDUSTRIES LTD.;TEVA PHARMACEUTICALS USA, INC.;DOLITZKY, BEN-ZION;PERLMAN, NURIT;KALUJNY, MARINA