发明名称 |
METHOD FOR DETECTING HUMAN CYTOCHROME P450 (CYP) 2D6 GENETIC VARIATIONS |
摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method that accurately measures the number of CYP2D6 genes, and thereby detects deficiency or duplication of CYP2D6 gene, that is simple and has high accuracy. <P>SOLUTION: In the detection of deficiency or duplication of CYP2D6 gene, a primer comprising a sequence which is complementary to a sequence that is common to CYP2D6 gene and CYP2D8 gene but is different from CYP2D7 gene and contains one or more bases at the 86 position, 90 position and 93 position of Exon 9 region of CYP2D6 gene is used. <P>COPYRIGHT: (C)2009,JPO&INPIT |
申请公布号 |
JP2009022191(A) |
申请公布日期 |
2009.02.05 |
申请号 |
JP20070187493 |
申请日期 |
2007.07.18 |
申请人 |
TOSHIBA CORP;PHARMACOGENE TIP-TOP INC |
发明人 |
NAKAMURA NAOKO;FUKUDA TAKASHI;AZUMA JUNICHI;MOTOMA NOBUHIRO |
分类号 |
C12Q1/68;C12M1/00;C12N15/09;G01N33/53 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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