发明名称 |
Deletion analogues of magainin peptides |
摘要 |
A compound comprising a deletion analogue of an amide or carboxy-terminating Magainin I of the following structural formula using the single letter amino acid code: <IMAGE> and wherein at least one of amino acid residues 15 through 23 is omitted; or a deletion analogue of an amide or carboxy-terminated Magainin II of the following structural formula using the single letter amino acid code: <IMAGE> and wherein at least one of amino acid residues 15 through 23 is omitted. These compounds can be effectively used as pharmaceutical compositions.
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申请公布号 |
US4962277(A) |
申请公布日期 |
1990.10.09 |
申请号 |
US19880281981 |
申请日期 |
1988.12.09 |
申请人 |
SCRIPPS CLINIC AND RESEARCH FOUNDATION |
发明人 |
CUERVO, JULIO H.;HOUGHTEN, RICHARD A. |
分类号 |
A61K38/00;A61K31/00;A61P15/00;A61P31/00;A61P31/12;A61P35/00;C07K7/08;C07K14/00;C07K14/46 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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