| 摘要 |
A compound selected from the group consisting of a compound of the formula <IMAGE> I wherein RA, R'A, RB and R'B are individually selected from the group consisting of hydrogen and alkyl of 1 to 4 carbon atoms or RA and R'A or RB and R'B together with the nitrogen atom to which they are attached form a 5- to 6-member heterocycle optionally substituted with alkyl of 1 to 3 carbon atoms and Y is hydrogen or <IMAGE> wherein R6 is selected from the group consisting of hydrogen, -CH3, -F and -Cl, R9 and R11 form a second bond at 9(11) or R9 is hydrogen or -F is hydrogen, -OH or =O, R16 is -CH3 or hydrogen, R17 is hydrogen, -OH or acyloxy, the dotted lines indicate the possible presence of a second bond at 1(2) and 6(7)-positions and the wavy line indicates the alpha - and beta -position and their non-toxic, pharmaceutically acceptable acid addition salts having anti-inflammatory and antioxidant activity.
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