<p>The present invention is directed towards a new method of synthesis of 18F-folate radiopharmaceuticals, wherein fluorine-18 is attached to a pteroate (or folate) or derivative thereof, through direct radiolabeling with 18 [F] fluoride, as well as 18F-folate radiopharmaceuticals obtained by such method of synthesis and their use in diagnosis and monitoring of cancer therapy and therapy of inflammatory and autoimmune diseases.</p>
申请公布号
WO2008125613(A1)
申请公布日期
2008.10.23
申请号
WO2008EP54404
申请日期
2008.04.11
申请人
MERCK EPROVA AG;AMETAMEY, SIMON MENSAH;MOSER, RUDOLF;ROSS, TOBIAS LUDWIG;PHOEBE, LAM;GROEHN, VIOLA
发明人
AMETAMEY, SIMON MENSAH;MOSER, RUDOLF;ROSS, TOBIAS LUDWIG;PHOEBE, LAM;GROEHN, VIOLA
