发明名称 |
Biopolymer automatic identifying method |
摘要 |
The invention aims to provide a highly accurate automatic biopolymer determination technique utilizing mass spectrometry whereby calibration prior to measurement or the addition of an internal standard to a sample can be eliminated. The biopolymer automatic identifying method of the invention comprises: retrieving a candidate molecule by matching an observed mass value X obtained by mass spectrometry with a predetermined database; selecting an arbitrary number of candidate molecules with high similarity scores; calibrating the observed mass value X using the candidate molecule as an internal standard; calculating relative error Ec between a calibrated mass value Xc and a theoretical mass value M of the candidate molecule; determining the standard deviation S<SUB>Ec </SUB>of the relative error; determining a tolerance Tc of database search from the standard deviation S<SUB>Ec</SUB>; and repeating a database search based on the tolerance Tc.
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申请公布号 |
US2006100792(A1) |
申请公布日期 |
2006.05.11 |
申请号 |
US20050526464 |
申请日期 |
2005.08.15 |
申请人 |
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE& TECHNOLOGY |
发明人 |
NATSUME TOHRU;NAKAYAMA HIROSHI |
分类号 |
H01J49/04 |
主分类号 |
H01J49/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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