发明名称 |
METHODS AND COMPOSITIONS FOR USE OF CYCLIC ANALOGUES OF HISTATIN |
摘要 |
Provided are novel compositions and therapeutic methods for treating bacterial and fungal disease with cyclic ana-logues of histatin. The cyclic analogues of histatin are advantageously more potent but less toxic than currently used anti-microbial agents. In addition, compositions comprising the cyclic analogue with other anti-microbial agents such as azole compounds are disclosed.
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申请公布号 |
CA2727939(A1) |
申请公布日期 |
2008.11.13 |
申请号 |
CA20082727939 |
申请日期 |
2008.05.05 |
申请人 |
THE UNIVERSITY OF WESTERN ONTARIO |
发明人 |
LAJOIE, GILLES ANDRE;VILK, GREG JOHN ADAMS;BREWER, DYANNE PATRICIA |
分类号 |
A61K38/12;A61K31/4174;A61K31/4196;A61K31/496;A61K31/506;A61P31/00;A61P31/04;A61P31/10;G01N33/53;G01N33/68 |
主分类号 |
A61K38/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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