Benzocycloheptapyridines as inhibitors of the receptor tyrosine kinase met

摘要

The present invention relates to 5H-benzo[4,5]cycloheptatriene [1,2-b]pyridine derivatives, that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.