| 摘要 |
A continuous intravenous analyte monitoring system includes an amperometr ic biosensor detecting an analyte concentration in the blood, a controller r eceiving a signal from the biosensor and computing the concentration, and an isolation device isolating the biosensor from EMl. A CPU may be coupled to the controller via the isolation device for continuous output of sensed conc entration to a display unit. Isolated circuits may include a temperature sen sor transmitting biosensor temperature to the controller for correction of t he computed concentration, a multiplexer combining biosensor and temperature sensor signals, and an A/D converter converting multiplexed input to the co ntroller. The biosensor may be a multi-electrode sensor having a working ele ctrode immobilizing an glucose oxidase enzyme to detect blood glucose concen tration. The biosensor and temperature sensor may be located in vivo using a catheter for continuous monitoring.
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