发明名称 |
Diagnostic markers of human female infertility |
摘要 |
The subject invention pertains to methods and reagents for the diagnosis of female infertility, prognostic indicators for female infertility, compounds for the treatment of female infertility, compounds and methods for contraception. Methods and compounds are based on the levels of ebaf in endometrial tissue. Methods for diagnosing endometrial receptivity and bleeding function by screening a biological sample such as an endometrial tissue sample, or bodily fluid for the presence of ebaf. A contraceptive compound containing an effective amount of ebaf and a pharmaceutically acceptable carrier. A diagnostic kit for timing contraception containing reagents for screening a sample for the presence of ebaf. A method of treating endometrial irregularities by down-regulating the expression of ebaf.
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申请公布号 |
US2008200379(A1) |
申请公布日期 |
2008.08.21 |
申请号 |
US20070796404 |
申请日期 |
2007.04.27 |
申请人 |
UNIVERSITY OF SOUTH FLORIDA |
发明人 |
TABIBZADEH SIAMAK;KOTHAPALLI RAVI |
分类号 |
A61K38/16;A61P15/08;C07K16/00;C12Q1/02;C12Q1/68;G01N33/53;G01N33/68 |
主分类号 |
A61K38/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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