| 摘要 |
FIELD: chemistry. ^ SUBSTANCE: claimed invention relates to method of obtaining 1-hydroxyadamanthan-4-on, which is immuno-stimulating means, efficient for treatment of limbs vascular system diseases of autoimmune genesis, chronic stomatitis, herpes, etc. Method lies in catalytic oxidation of adamanthon-2. Here as oxidant agent, hydrobromous acid is used, which is generated in situ from carbon tetrabromide and water, and oxidation is performed in presence of catalysts - compounds of molybdenum Mo(CO)6 or tungsten W(CO)6, with molar ratio[Mo(CO)6 or W(CO)6]: [adamanthon-2]:[CBr4]:[H2O]=1:100:100:1000-4000 at temperature 140-160°C during 6-10 hours. ^ EFFECT: obtaining 1-hydroxyadamanthan-4-on with high output, with simplification and cheapening technology. ^ 1 tbl, 1 ex |
