发明名称 CONSTITUTIVE GENE EXPRESSION IN CONJUNCTION WITH IONIZING RADIATION
摘要 The present disclosure demonstrates the successful use of constitutive promoters operatively linked to genes encoding radiosensitizing or radioprotecting factors, administered to cells, tissues, or patients in conjunction with radiation exposure. Also disclosed are pharmacological preparations to be used to increase the levels of radiosensitizing compounds such as TNF-alpha, or radioprotective compounds such as MnSOD, in specified tissues or tumors of a subject.
申请公布号 US2008118471(A1) 申请公布日期 2008.05.22
申请号 US20080019428 申请日期 2008.01.24
申请人 DANA-FARBER CANCER INSTITUTE;ARCH DEVELOPMENT CORPORATION 发明人 WEICHSELBAUM RALPH R.;HALLAHAN DENNIS E.;KUFE DONALD W.;SUKHATME VIKAS P.
分类号 A61K48/00 主分类号 A61K48/00
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