发明名称 |
СПОСОБ ЛЕЧЕНИЯ ИНСУЛЬТА С ПРИМЕНЕНИЕМ ВВЕДЕНИЯ ДЕФИБРИНОГЕНИЗИРУЮЩИХ СРЕДСТВ ДЛЯ ДОСТИЖЕНИЯ СПЕЦИФИЧЕСКОГО ХАРАКТЕРА ДЕФИБРИНОГЕНИЗАЦИИ |
摘要 |
The present invention provides a method for the treatment of acute ischemic stroke based on a specific rate and pattern of defibrinogenation and subsequent refibrogenation associated with optimized efficacy and significantly improved safety. The administration of a single dose of defibrinogenating agent to achieve an optimal rate of defirinogenation avoids prolonged hypofibrinogenenemia and concomitant adverse side effects such as intracranial hemorrhage. The defibrinogenating agent is administered as a single dose and time-weighted end of treatment fibrinogen levels of >70 mg/dL are achieved by simply stopping administration of the defibrinogenating agent. |
申请公布号 |
RU2006138043(A) |
申请公布日期 |
2008.05.10 |
申请号 |
RU20060138043 |
申请日期 |
2005.03.30 |
申请人 |
НОЙРОБАЙЛОДЖИКАЛ ТЕКНОЛОДЖИЗ, ИНК. (US) |
发明人 |
ПЕТТИ Стефен Дж. (US);ПЕТТИ Самн Раффаньелло (US) |
分类号 |
A61K35/39;A61K35/58;A61K38/48 |
主分类号 |
A61K35/39 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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