METHOD FOR PREPARING RIFABUTIN-CONTAINING ANTIBACTERIAL COMPOSITION

摘要

FIELD: pharmaceutical industry and technology, pharmacy. ^ SUBSTANCE: invention relates to development of method for preparing rifabutin-containing antibacterial composition. Method involves separate mixing one part of rifabutin with special additives and filling agent and another part of rifabutin with lacking amount of filling agent and their following combining, powdering the mixture with magnesium stearate at stirring and making capsules. Method allows simplifying technology in preparing the preparation in capsulated form owing to optimal technological indices of the prepared composition mixture. The composition shows high stability in storing and therapeutic effectiveness. ^ EFFECT: valuable pharmaceutical and medicinal properties of composition. ^ 2 tbl, 1 ex