| 摘要 |
<p>An ophthalmic insert (24) and method for sustained release of medication to the eye are provided. The insert (24) includes a body portion (30) sized to pass through a lacrimal punctum (14, 16) and be positioned within a lacrimal canaliculus (18, 20) of the eyelid. The insert further includes a collarette (26) connected to the body portion (30) and sized to rest on the exterior of the lacrimal punctum, the collarette having a pore (42) provided therein. A reservoir (34) is contained at least partially within the body portion (30) and in fluid communication with the pore (42), wherein the reservoir (34) is designed to store and release medication through the pore (42) and onto the eye over time in a controlled manner while the insert (24) is positioned in the eyelid. Preferably, the pore (42) is constructed with a specific geometry appropriate to control the rate of release of the medication onto the eye.</p> |
